Publications

    In Press

  1. P Samant, MR Prausnitz, Mechanisms of sampling interstitial fluid from skin using a microneedle patch, Proceedings of the National Academy of Sciences, (in press).
  2. JC Joyce, TD Carroll, ML Collins, M Chen, L Fritts, JC Dutra, TL Rourke, JL Goodson, MB McChesney, MR Prausnitz, PA Rota, A microneedle patch for measles and rubella vaccination is immunogenic and protective in infant rhesus macaques, Journal of Infectious Diseases, (in press).
  3. B Chiang, JH Jung, MR Prausnitz, The suprachoroidal space as a route of administration to the posterior segment of the eye, Advanced Drug Delivery Reviews, (in press).
  4. SY Holguin, MD Gray, P Joseph, NN Thadhani, MR Prausnitz, Photoporation using carbon nanotubes for intracellular delivery of molecules and its relationship to photoacoustic pressure, Advanced Healthcare Materials, (in press).
  5. 2018

  6. M Niedzwiecki, P Samant, DI Walker, V Tran, DP Jones, MR Prausnitz, GW Miller (2018), Human suction blister fluid composition determined using high-resolution metabolomics, Analytical Chemistry, 90:3786-3792. [PubMed link]
  7. JH Jung, B Chiang, HE Grossniklaus, MR Prausnitz, I Skountzou (2018) Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle, Journal of Controlled Release, 227:14-22. [PubMed link]
  8. EQ Littauer, LK Mills, N Brock, ES Esser, A Romanyuk, JA Pulit-Penaloza, EV Vassilieva, JT Beaver, F Krammer, RW Compans, MR Prausnitz, I Skountzou (2018) Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza, Journal of Controlled Release, 276:1-16. [PubMed link]
  9. TK Resch, Y Wang, SS Moon, J Joyce, S Li, MR Prausnitz, B Jiang (2018) Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice, Scientific Reports, 8:561. [PubMed link]
  10. 2017

  11. EV Vassilieva, S Wang, S Li, MR Prausnitz, RW Compans (2017) Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine, Scientific Reports, 7:17855. [PubMed link]
  12. C Tas, JC Joyce, HX Nguyen, P Eangoor, JS Knaack, AK Banga, MR Prausnitz (2017) Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy, Journal of Controlled Release, 268:159-165. [PubMed link]
  13. ES Esser, JA Pulit-Penaloza, H Kalluri, D McAllister, EV Vassilieva, EQ Littauer, N Lelutiu, MR Prausnitz, RW Compans, I Skountzou (2017) Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring, Scientific Reports, 7:5705. [PubMed link]
  14. SY Holguin, CF Anderson, NN Thadhani, MR Prausnitz (2017) Role of cytoskeletal mechanics and cell membrane fluidity in the intracellular delivery of molecules mediated by laser-activated carbon nanoparticles, Biotechnology and Bioengineering, 114:2390-2399. [PubMed link]
  15. W Zhu, WP Pewin, C Wang, Y Luo, GX Gonzalez, T Mohan, MR Prausnitz, BZ Wang (2017) A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines, Journal of Control Release, 261:1-9. [PubMed link]
  16. NG Rouphael, M Paine, R Mosley, S Henry, DV McAllister, H Kalluri, WP Pewin, PM Frew, T Yu, NJ Thornburg, S Kabbani, L Lai, EV Vassilieva, I Skountzou, RW Compans, MJ Mulligan, MR Prausnitz (2017) The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial, The Lancet, 390:649-658. [PubMed link]
  17. MR Prausnitz (2017) Engineering microneedle patches for vaccination and drug delivery to skin, Annual Review of Chemical and Biomolecular Engineering, 8:177-200. [PubMed link]
  18. A Sengupta, MD Gray, SC Kelly, SY Holguin, NN Thadhani, MR Prausnitz (2017) Energy transfer mechanisms during molecular delivery to cells by laser-activated carbon nanoparticles, Biophysical Journal, 112:1258-1269. [Cell link]
  19. B Chiang, K Wang, CR Ethier, MR Prausnitz (2017) Clearance kinetics and clearance routes of molecules from the suprachoroidal space after microneedle injection, Investigative Ophthalmology and Visual Science, 58:545-554. [PubMed link]
  20. B Chiang, N Venugopal, HE Grossniklaus, JH Jung, HF. Edelhauser, MR Prausnitz (2017) Thickness and closure kinetics of the suprachoroidal space following microneedle injection of liquid formulations, Investigative Ophthalmology and Visual Science, 58:555-564. [PubMed link]
  21. J Arya, S Henry, H Kalluri, DV McAllister, WP Pewin, MR Prausnitz (2017) Tolerability, usability and acceptability of dissolving microneedle patch administration in human subjects, Biomaterials, 128:1-7. [PubMed link]
  22. MJ Mistilis, JC Joyce, ES Esser, I Skountzou, RW Compans, AS Bommarius, MR Prausnitz (2017) Long-term stability of influenza vaccine in a dissolving microneedle patch, Drug Delivery and Translational Research, 7:195-205. [PubMed link]
  23. JO Morales, K. Fathe, A Brunaugh, S Ferrati, S Li, M Montenegro-Nicolini, Z Mousavikhamene, JT McConville, MR Prausnitz (2017) HDC smyth, challenges and future prospects for the delivery of biologics: oral Mucosal, pulmonary, and transdermal routes, AAPS Journal, 19:652-668. [PubMed link]
  24. HW Yang, L Ye, XD Guo, C Yang, RW Compans, MR Prausnitz (2017) Ebola vaccination using a DNA vaccine coated on PLGA-PLL/γPGA nanoparticles administered using a microneedle patch, Advanced Healthcare Materials, 6:1600750. [PubMed link]
  25. 2016

  26. P Chakravarty, CD Lane, TM Orlando, MR Prausnitz (2016) Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles, Nanomedicine, 12:1003-1111. [Pubmed link]
  27. SR Patel, MR Prausnitz (2016) Targeted drug Delivery within the eye through the suprachoroidal space, Journal of Ocular Pharmacology and Therapeutics, 32:640-641. [Liebertpub link]
  28. B Chiang, N Venugopal, HF Edelhauser, MR Prausnitz (2016) Distribution of particles, small molecules and polymeric formulation excipients in the suprachoroidal space after microneedle injection, Experimental Eye Research, 153:101-109. [PubMed link]
  29. J Arya, K Dewitt, M Scott-Garrard, Y Chiang, MR Prausnitz (2016) Rabies vaccination in dogs using a dissolving microneedle patch, Journal of Controlled Release, 240:135-141. [PubMed link]
  30. J Arya, MR Prausnitz (2016) Microneedle patches for vaccination in developing countries, Journal of Controlled Release, 239:19-26. [PubMed link]
  31. ES Esser , A Romanyuk , EV Vassilieva , J Jacob , MR Prausnitz, RW Compans, I Skountzou (2016) Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy, Journal of Controlled Release, 236:135-141. [PubMed link]
  32. B Chiang, YC Kim, AC Doty, HE Grossniklaus, SP Schwendeman, MR Prausnitz (2016) Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma, Journal of Controlled Release, 228:48-57. [PubMed link]
  33. Y Liu, J Yan, PJ Santangelo, MR Prausnitz (2016) DNA uptake, intracellular trafficking and gene transfection after ultrasound exposure, Journal of Controlled Release, 234:1-9. [PubMed link]
  34. B Chiang, YC Kim, HF Edelhauser, MR Prausnitz (2016) Circumferential flow of particles in the suprachoroidal space is impeded by the posterior ciliary arteries, Experimental Eye Research, 145:424-31. [PubMed link]
  35. LY Chu, L Ye, K Dong, RW Compans, C Yang, MR Prausnitz (2016) Enhanced stability of inactivated influenza vaccine encapsulated in dissolving microneedle patches, Pharmaceutical Research, 33:868-878. [PubMed link]
  36. S Park, SO Choi, SJ Paik, S Choi, M Allen, MR Prausnitz (2016) Intracellular delivery of molecules using microfabricated nanoneedle arrays, Biomedical Microdevices, 18:10. [PubMed link]
  37. 2015

  38. MJ Uddin, N Scoutaris, P Klepetsanis, B Chowdry, MR Prausnitz, D Douroumis (2015) Inkjet printing of transdermal microneedles for the delivery of anticancer agents, International Journal of Pharmaceutics, 494:593-602. [PubMed link]
  39. YC Kim, KH Oh, HF Edelhauser, MR Prausnitz (2015) Formulation to target delivery to the ciliary body and choroid via the suprachoroidal space of the eye using microneedles, European Journal of Pharmaceutics and Biopharmaceutics, 95:398-406. [PubMed link]
  40. HJ Choi, JM Song, BJ Bondy, RW Compans, SM Kang, MR Prausnitz (2015) Effect of osmotic pressure on the stability of whole inactivated influenza vaccine for coating on microneedles, PLoS ONE, 10:e0134431. [PubMed link]
  41. MR Prausnitz (2015) Puncturing cells en masse, Nature Materials, 14:470-471. [PubMed link]
  42. A Sengupta, R Mezencev, JF McDonald, MR Prausnitz (2015) Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles, Nanomedicine (Lond), 10:1775-84. [PubMed link]
  43. DG Koutsonanos, ES Esser, SR McMaster, P Kalluri, JW Lee, MR Prausnitz, I Skountzou, TL Denning, JE Kohlmeier, RW Compans (2015) Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts, Vaccine, 33:4675-4682. [PubMed link]
  44. BY Lee, SM Bartsch, M Mvundura, C Jarrahian, KM Zapf, K Marinan, AR Wateska, B Snyder, S Swaminathan, E Jacoby, JJ Norman, MR Prausnitz, D Zehrung (2015) An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine, Vaccine, 33:4727-4736. [PubMed link]
  45. WC Edens, NC Dybdahl-Sissoko, WC Weldon, MS Oberste, MR Prausnitz (2015) Inactivated polio vaccination using a microneedle patch is immunogenic in the rhesus macaque, Vaccine, 33:4683-4690. [PubMed link]
  46. WC Edens, ML Collins, JL Goodson, PA Rota, MR Prausnitz (2015) A microneedle patch containing measles vaccine is immunogenic in non-human primates, Vaccine, 33:4712-4718. [PubMed link]
  47. EV Vassilieva, H Kalluri, D McAllister, MT Taherbhai, ES Esser, WP Pewin, JA Pulit-Penaloza, MR Prausnitz, RW Compans, I Skountzou (2015) Improved immunogenicity of individual influenza vaccine components delivered with a novel dissolving microneedle patch stable at room temperature, Drug Delivery and Translational Research, 5:360-71. [PubMed link]
  48. HJ Park, MR Prausnitz (2015) Lidocaine-ibuprofen ionic liquid for dermal anesthesia, American Institute of Chemical Engineers Journal, 61:2732-2738.
  49. MC Kim, JW Lee, HJ Choi, YN Lee, HS Hwang, J Lee, C Kim, JS Lee, C Montemagno, MR Prausnitz, SM Kang (2015) Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection, Journal of Controlled Release, 210:208-216. [PubMed link]
  50. A Sengupta, N Dwivedi, SC Kelly, L Tucci, NN Thadhani, MR Prausnitz (2015) Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells, Biotechnology and Bioengineering, 4:126-30. [PubMed link]
  51. RC Kines, V Zarnitsyn, TR Johnson, YY Pang, KS Corbett, JD Nicewonger, A Gangopadhyay, M Chen, J Liu, MR Prausnitz, JT Schiller, BS Graham (2015) Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles, PLoS One, 10:e0120797. [PubMed link]
  52. MJ Mistilis, AS Bommarius, MR Prausnitz (2015) Development of a thermostable microneedle patch for influenza vaccination, Journal of Pharmaceutical Sciences, 104:740-749. [PubMed link]
  53. 2014

  54. A Romanyuk, V Zvezdin, P Samant, M Grenader, M Zemlyanova, MR Prausnitz (2014) Collection of analytes from microneedle patches, Analytical Chemistry, 86:10520-10523. [PubMed link]
  55. JJ Norman, J Gupta, SR Patel, S Park, C Jarrahian, D Zehrung, MR Prausnitz (2014) Reliability and accuracy of intradermal injection by mantoux technique, hypodermic needle adapter, and hollow microneedle in pigs, Drug Delivery and Translational Research, 4:126-30. [PubMed link]
  56. YC Kim, HE Grossniklaus, HF Edelhauser, MR Prausnitz (2014) Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization, Investigative Ophthalmology and Visual Science, 55:7376-86. [PubMed link]
  57. YC Kim, HF Edelhauser, MR Prausnitz (2014) Targeted delivery of antiglaucoma drugs to the supraciliary space using microneedles, Investigative Ophthalmology and Visual Science, 55:7387-97. [PubMed link]
  58. YC Kim, B Chiang, X Wu, MR Prausnitz (2014) Ocular delivery of macromolecules, Journal of Controlled Release, 190:172-181. [PubMed link]
  59. YC Kim, HF Edelhauser, MR Prausnitz (2014) Particle-stabilized emulsion droplets for gravity-mediated targeting in the posterior segment of the eye, Advanced Healthcare Materials, 3:1272-82. [PubMed link]
  60. J Pulit-Penaloza, ES Esser, E Vassilieva, JW Lee, M Taherbhai, B Pollack, MR Prausnitz, RW Compans, I Skountzou (2014) A protective role of murine langerin+ cells in immune responses to cutaneous vaccination with microneedle patches, Scientific Reports, 4:6094. [PubMed link]
  61. A Sengupta, SC Kelly, N Dwivedi, N Thadhani, MR Prausnitz (2014) Efficient intracellular delivery of molecules with high cell viability using nanosecond-pulsed laser-activated carbon nanoparticles, ACS Nano, 8:2889-8299. [PubMed link]
  62. JJ Norman, JM Arya, MA McClain, PM Frew, MI Meltzer, MR Prausnitz (2014) Microneedle patches: usability and acceptability for self-administration against influenza, Vaccine, 32:1856-1862. [PubMed link]
  63. BZ Wang, HS Gill, C He, C Ou, L Wang, YC Wang, H Zhang, MR Prausnitz, RW Compans (2014) Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity, Journal of Controlled Release,178:1-7. [PubMed link]
  64. 2013

  65. YC Kim, DG Yoo, RW Compans, SM Kang, MR Prausnitz (2013) Cross-protection by co-immunization with influenza hemagglutinin DNA and inactivated virus vaccine using coated microneedles, Journal of Controlled Release, 172:579-588. [PubMed link]
  66. JJ Norman, MR Brown, NA Raviele, MR Prausnitz, EI Felner (2013) Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes, Pediatric Diabetes, 14:459-465. [PubMed link]
  67. FS Quan, YC Kim, JM Song, HS Hwang, RW Compans, MR Prausnitz, SM Kang (2013) Long-term protective immunity from an influenza virus-like particle vaccine administered with a microneedle patch, Clinical Vaccine Immunology, 20:1433-1439. [PubMed link]
  68. D Wing, MR Prausnitz, MJ Buono (2013) Skin pretreatment with microneedles prior to pilocarpine iontophoresis increases sweat production, Clin Physiol Funct Imaging, 33:436-440. [PubMed link]
  69. S Moon, Y Wang, C Edens, J Gentsch, MR Prausnitz, B Jiang (2013) Dose sparing and enhanced immunogenicity of inactivated rotavirus vaccine administered by skin vaccination using a microneedle patch, Vaccine, 31:3396-3402. [PubMed link]
  70. C Edens, ML Collins, J Ayers, PA Rota, MR Prausnitz (2013) Measles vaccination using a microneedle patch, Vaccine, 31:3403-3409. [PubMed link]
  71. JJ Norman, SO Choi, NT Tong, AR Aiyar, SR Patel, MR Prausnitz, MG Allen (2013) Hollow microneedles for intradermal injection fabricated by sacrificial micromolding and selective electrodeposition, Biomedical Microdevices, 15:203-210. [PubMed link]
  72. SN Andrews, E Jeong, MR Prausnitz (2013) Transdermal delivery of molecules is limited by full epidermis, not just statum corneum, Pharmaceutical Research, 30:1099-1109. [PubMed link]
  73. HJ Choi, DG Yoo, B Bondy, FS Quan, RW. Compans, SM Kang, MR Prausnitz, Stability of whole inactivated influenza virus vaccine during coating onto metal microneedles (2013) Journal of Controlled Release, 166:159-171. [PubMed link]
  74. BM Torrisi, VG Zarnitsyn, MR Prausnitz,, A Anstey, C Gateley, JC Birchall, SA Coulman (2013) Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin. Journal of Controlled Release, 165:146-52. [PudMed link]
  75. 2012

  76. C Tas, S Mansoor, A Banga, MR Prausnitz (2012) Development and validation of a rapid isocratic RP-HPLC method for the quantification of salmon calcitonin, Turkish Journal of Pharmaceutical Sciences, 9:323-334.
  77. WC Weldon, VG Zarnitsyn, ES Esser, MT Taherbhai, DG Koutsonanos, EV Vassilieva, I Skountzou, MR Prausnitz, RW Compans (2012) Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine. PLoS One, 7:e41501. [PubMed link]
  78. B Aytar, MR Prausnitz, DM Lynn (2012) Rapid release of plasmid DNA from surfaces coated with polyelectrolyte multilayers promoted by the application of electrochemical potentials, ACS Applied Materials Interfaces, 4:2726-2734. [PubMed link]
  79. M Park, CG Park, SH Lee, JE Lee, E Cho, MR Prausnitz, YB Choy (2012) Polymeric tube-shaped devices with controlled geometry for programmed drug delivery, Macromolecular Research, 20:960-967.
  80. YC Kim, JH Park, MR Prausnitz (2012) Microneedles for drug and vaccine delivery, Advanced Drug Delivery Reviews, 64:1547-1568. [PudMed link]
  81. XD Guo, MR Prausnitz (2012) Microelectronic control of drug delivery, Expert Review of Medical Devices, 9:323-326. [PubMed link]
  82. MR Prausnitz , PM Elias, TJ Franz, M Schmuth, J-C Tsai, GK Menon, WM Holleran, KR Feingold (2012) Skin barrier and transdermal drug delivery, Dermatology, 3 ed.; J Bolognia, J Jorizzo, J Schaffer, Eds. Elsevier Health Sciences.
  83. JM Song, YC Kim, E O, RW Compans, MR Prausnitz, SM Kang (2012) DNA vaccination in the skin using microneedles improves protection against influenza, Molecular Therapy, 20:1472-1480. [PubMed link]
  84. SR Patel , DE Berezovsky , BE McCarey , V Zarnitsyn , HF Edelhauser, MR Prausnitz (2012) Targeted administration into the suprachoroidal space using a microneedle for drug delivery to the posterior segment of the eye, Investigative Ophthalmology Visual Science, 53:4433-4441. [PubMed link]
  85. Y Liu, NJ Bowen, L Matyunina, J McDonald, MR Prausnitz (2012) Gene transfection enhanced by ultrasound exposure combined with drug treatment guided by gene chip analysis, International Journal of Hyperthermia, 28(4):349-361. [PubMed link]
  86. YC Kim, JM Song, AS Lipatov, SO Choi, JW Lee, RO Donis, RW Compans, SM Kang, MR Prausnitz (2012) Increased immunogenicity of avian influenza DNA vaccine delivered to the skin using a microneedle patch, European Journal of Pharmaceutics and Biopharmaceutics, 81:239-247. [PubMed link]
  87. JJ Norman, MR Prausnitz (2012) Improving patient acceptance of insulin therapy by improving needle design, Journal of Diabetes Science and Technology, 6:336-338. [PubMed link].
  88. DG Koutsonanos, EV Vassilieva, A Stavropoulou, VG Zarnitsyn, ES Esser, MT Taherbhai, MR Prausnitz, RW Compans, I Skountzou (2012) Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection, Scientific Reports, 2:357. [PubMed link]
  89. SH Lee, M Park, CG Park, JE Lee, MR Prausnitz, YB Choy (2012) Microchip for sustained drug delivery by diffusion through microchannels, AAPS PharmSciTech, 13:211-7. [PubMed link]
  90. SO Choi, YC Kim, JW Lee, JH Park, MR Prausnitz, MG Allen (2012) Intracellular protein delivery and gene transfection by electroporation using a microneedle electrode array, Small, 8:1081-1091. [PubMed link]
  91. MP Martin, WC Weldon, VG Zarnitsyn, DG Koutsonanos, H Akbari, I Skountzou, J Jacob, MR Prausnitz, RW Compans (2012) Local response to microneedle-based influenza immunization in the skin, mBio, 3:e00012-12. [PubMed link]
  92. HJ Choi, DG Yoo, B Bondy, FS Quan, RW Compans, SM Kang, MR Prausnitz (2012) Stability of influenza vaccine coated onto microneedles, Biomaterials, 33:3756-3769. [PubMed link]
  93. Y Liu, J Yan, MR Prausnitz, Can ultrasound enable efficient intracellular uptake of molecules? A retrospective literature review and analysis, Ultrasound in Medicine and Biology, 38:876-888. [PubMed link]
  94. YC Kim, C Jarrahian, D Zehrung, S Mitragotri, MR Prausnitz (2012) Delivery systems for intradermal vaccination, Current Topics in Microbiology and Immunology, 351:77-112. [PubMed link]
  95. J Gupta, DD Denson, EI Felner, MR Prausnitz (2012) Rapid local anesthesia in human subjects using minimally invasive microneedles, Clinical Journal of Pain, 28:129-135. [PubMed link]
  96. C Tas, S Mansoor, H Kalluri, VG Zarnitsyn, SO Choi, AK Banga, MR Prausnitz (2012) Delivery of salmon calcitonin using a microneedle patch, International Journal of Pharmaceutics, 423:257-263. [PubMed link]
  97. 2011

  98. JJ Norman, SN Andrews, MR Prausnitz (2011) Undergraduate laboratory module on skin diffusion Chemical Engineering Education, 45: 276-282.
  99. SR Patel, HR Edelhauser, MR Prausnitz (2011) Targeted drug delivery to the eye enabled by microneedles, Drug Product Development for the Back of the Eye, 331-361. [Springer link]
  100. SN Andrews, JW Lee, MR Prausnitz (2011) Recovery of skin barrier after stratum corneum removal by microdermabrasion, AAPS PharmSciTech, 12:1393-1400. [PubMed link]
  101. SN Andrews, JW Lee, SO Choi, MR Prausnitz (2011) Transdermal insulin delivery using microdermabrasion, Pharmaceutical Research, 28:2110-2118. [PubMed link]
  102. DG Koutsonanos, MP Martin, VG Zarnitsyn, J Jacob, MR Prausnitz, RW Compans, I Skountzou (2011) Serological memory and long-term protection to novel H1N1 influenza virus after skin vaccination, Journal of Infectious Diseases, 204:582-591. [PubMed link]
  103. E González-González, YC Kim, TJ Speaker, RP Hickerson, R Spitler, JC Birchall, MF Lara, RH Hu, Y Liang, N Kirkiles-Smith, MR Prausnitz, CH Contag, LM Milstone, RL Kaspar (2011) Visualization of plasmid delivery to keratinocytes in mouse and human epidermis, Scientific Reports, 1:158. [PubMed link]
  104. C Baek, MR Han, J Min, MR Prausnitz, J-H Park, J Park (2011) Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles, Journal of Controlled Release, 154:138-147. [PubMed link]
  105. J Gupta, HS Gill, SN Andrews, MR Prausnitz (2011) Kinetics of skin resealing after insertion of microneedles in human subjects, Journal of Controlled Release,154:148-155. [PubMed link]
  106. JW Lee, P Gadiraju, J-H Park, MG Allen, MR Prausnitz (2011) Microsecond thermal ablation of skin for transdermal drug delivery, Journal of Controlled Release, 154:58-68. [PubMed link]
  107. J Gupta, S Park, B Bondy, EI Felner, MR Prausnitz (2011) Infusion pressure and pain during microneedle injection into skin of human subjects, Biomaterials, 32:6823-6831. [PubMed link]
  108. MR Prausnitz, AS Bommarius (2011) Drug design, development and delivery: an interdisciplinary course on pharmaceuticals, Chemical Engineering Education, 45:47-52.
  109. YB Choy, SR Patel, JH Park, BE McCarey, HF Edelhauser, MR Prausnitz (2011) Mucoadhesive microparticles in a rapidly-dissolving tablet for sustained drug delivery to the eye, Investigative Ophthalmology & Visual Science, 52:2627-2633. [PubMed link]
  110. WC Weldon, MP Martin, V Zarnitsyn, B Wang, D Koutsonanos, I Skountzou, MR Prausnitz, RW Compans (2011) Microneedle vaccination with stabilized recombinant influenza hemagglutinin induces improved protective immunity, Clinical and Vaccine Immunology, 18:647-654. [PubMed link]
  111. YB Choy, MR Prausnitz (2011) The rule of five for non-oral routes of drug delivery:  ophthalmic, inhalation and transdermal, Pharmaceutical Research, 28(5):943-948. [PubMed link]
  112. J Gupta, EI Felner, MR Prausnitz (2011) Rapid pharmacokinetics of intradermal insulin administered using microneedles in type 1 diabetes subjects, Diabetes Technology and Therapeutics ,13:451-456. [PubMed link]
  113. SN Andrews, V Zarnitsyn, B Bondy, MR Prausnitz (2011) Optimization of Microdermabrasion for Controlled Removal of Stratum Corneum, International Journal of Pharmaceutics, 407:95-104. [PubMed link]
  114. Y Hiraishi, S Nandakumar, SO Choi, JW Lee, YC Kim, JE Posey, SB Sable, MR Prausnitz (2011) Bacillus Calmette-Guérin vaccination using a microneedle patch, Vaccine, 29:2626-2636. [PubMed link]
  115. JW Lee, SO Choi, EI Felner, MR Prausnitz (2011) Dissolving microneedle patch for transdermal delivery of human growth hormone, Small, 7:531-539. [PubMed link]
  116. LY Chu, MR Prausnitz (2011) Separable arrowhead microneedles, Journal of Controlled Release, 149:242-9. [PubMed link]
  117. YK Yoon, JH Park, JW Lee, MR Prausnitz, MG Allen (2011) Thermal microjet system with tapered micronozzles fabricated by inclined UV lithography for transdermal drug delivery, Journal of Micromechanics and Microengineering, 21:025014. [IOP link]
  118. YC Kim, MR Prausnitz (2011) Enabling skin vaccination using new delivery technologies, Drug Delivery and Translational Research, 1:7-12. [PubMed link]
  119. SR Patel, ASP Lin, HF Edelhauser, MR Prausnitz (2011) Suprachoroidal drug delivery to the back of the eye using hollow microneedles, Pharmaceutical Research, 28:166-176. [PubMed link]
  120. YC Kim, FS Quan, RW Compans, SM Kang, MR Prausnitz (2011) Stability kinetics of influenza vaccine coated onto microneedles during drying and storage, Pharmaceutical Research, 28:135-144. [PubMed link]
  121. 2010

  122. EM Saurer; RM Flessner, SP Sullivan, MR Prausnitz, DM Lynn (2010) Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin, Biomacromolecules, 11:3136-3143. [PubMed link]
  123. MR Prausnitz (2010) Three generations of transdermal drug delivery, Experimental Dermatology, 19:950-951.
  124. YC Kim, PJ Ludovice, MR Prausnitz (2010) Transdermal delivery enhanced by antimicrobial peptides, Journal of Biomedical Nanotechnology, 6:612-620 [PubMed link]
  125. Y Liu, S Paliwal, KS Bankiewicz, JR Bringas, G Heart, S Mitragotri, MR Prausnitz (2010) Ultrasound-enhanced drug transport and distribution in the brain, AAPS PharmSciTech, 11:1005-1017. [PubMed link]
  126. YC Kim, F-S Quan, RW Compans, S-M Kang, MR Prausnitz (2010) Formulation of microneedles coated with influenza virus-like particle vaccine, AAPS PharmSciTech, 11:1193-1201. [PubMed link]
  127. FS Quan, YC Kim, RW Compans, MR Prausnitz, SM Kang (2010) Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles, Journal of Control Release, 147:326-332. [PubMed link]
  128. JH Park, SO Choi, S Seo, YB Choy, MR Prausnitz (2010) A microneedle roller for transdermal drug delivery, European Journal of Pharmaceutics and Biopharmaceutics, 76:282-289. [PubMed link]
  129. LY Chu, SO Choi, MR Prausnitz, Fabrication of dissolving polymer microneedles for controlled drug encapsulation and delivery: bubble and pedestal microneedle designs (2010) Journal of Pharmaceutical Sciences, 99:4228-4238. [PubMed link]
  130. JM Song, YC Kim, PG Barlow, MJ Hossain, KM Park, RO Donis, MR Prausnitz, RW Compans, SM Kang (2010) Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles, Antiviral Research, 88:244-247. [PubMed link]
  131. JM Song, YC Kim, AS Lipatov, M Pearton, CT Davis, DG Yoo, KM Park, LM Chen, FS Quan, J Birchall, RO Donis, MR Prausnitz, RW Compans, SM Kang (2010) Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B and T cell responses in mice,  Clinical and Vaccine Immunology, 17:1381-1389. [PubMed link]
  132. M Pearton, S-Moo Kang, J-Min Song, Y-C Kim, F-S Quan, A Anstey, M Ivory, MR Prausnitz, RW Compans, JC Birchall (2010) Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin, Vaccine, 28:6104-6113. [PubMed link]
  133. P Chakravarty, W Qian, MA El-Sayed, MR Prausnitz (2010) Delivery of molecules into cells using carbon nanoparticles activated by femtosecond laser pulses, Nature Nanotechnology, 5:607-611. [PubMed link]
  134. SP Sullivan, DG Koutsonanos, MP Martin, JW Lee, V Zarnitsyn, SO Choi, N Murthy, RW Compans, I Skountzou, MR Prausnitz (2010), Dissolving polymer microneedle patches for influenza vaccination, Nature Medicine, 16:915-921. [PubMed link]
  135. FS Quan, YC Kim, A Vunnava, DG Yoo, JM Song, MR Prausnitz, RW Compans, SM Kang (2010) Intradermal vaccination with influenza virus-like particles by using microneedles induces protection superior to that with intramuscular immunization, Journal of Virology, 84:7760-7769. [PubMed link]
  136. HS Gill, J Sõderholm, MR Prausnitz, M Sãllberg (2010) Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine, Gene Therapy, 17:811-814. [PubMed link]
  137. SL Banks, RR Pinninti, HS Gill, KS Paudel, PA Crooks, NK Brogden, MR Prausnitz, AL Stinchcomb (2010) Transdermal delivery of naltrexol and skin permeability lifetime after microneedle treatment in hairless guinea pigs in vivo, Journal of Pharmaceutical Sciences, 99:3072-3080. [PubMed link]
  138. YC Kim, FS Quan, RW Compans, SM Kang, MR Prausnitz (2010) Formulation and coating of microneedles with inactivated influenza virus to improve vaccine stability and immunogenicity, Journal of Controlled Release, 142:187-195. [PubMed link]
  139. JD Hutcheson, RK Schlicher, HK Hicks, MR Prausnitz (2010), Saving cells from ultrasound-induced apoptosis: quantification of cell death and uptake following sonication and effects of targeted calcium chelation, Ultrasound in Medicine and Biology, 36:1008-1021. [PubMed link]
  140. YC Kim, FS Quan, JM Song, A Vunnava, DG Yoo, KM Park, RW Compans, SM Kang, MR Prausnitz (2010) Influenza immunization with trehalose-stabilized virus-like particle vaccination using microneedles, Procedia in Vaccinology, 2:17-21.
  141. SO Choi, YC Kim, JH Park, J Hutcheson, HS Gill, YK Yoon, MR Prausnitz, MG Allen (2010) An electrically active microneedle array for electroporation, Biomedical Microdevices, 12:263-273. [PubMed link]
  142. JH Park, MR Prausnitz (2010) Analysis of mechanical failure of polymer microneedles by axial force (2010) Journal of the Korean Physical Society, 56:1223-1227. [PubMed link]
  143. RK Schlicher, JD Hutcheson, H Radhakrishna, RP Apkarian, MR Prausnitz (2010), Changes in cell morphology due to plasma membrane wounding by acoustic cavitation, Ultrasound in Medicine and Biology, 36:677-692. [PubMed link]
  144. AK Andrianov, DP DeCollibus, HA Gillis, HH Khaa, A Marin, MR Prausnitz, LA Babiuk, H Townsend, G Mutwirid (2010) Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization, Proceedings of the National Academy of Sciences, (USA) 106:18936-18941. [PubMed link]
  145. YC Kim, FS Quan, DG Yoo, RW Compans, SM Kang, MR Prausnitz (2010) Enhanced memory responses to H1N1 influenza vaccination in the skin using vaccine-coated microneedles, Journal of Infectious Diseases, 201:190-198. [PubMed link]
  146. 2009

  147. MR Prausnitz, JA Mikszta, M Cormier, AK Andrianov (2009) Microneedle-based vaccines, Current Topics in Microbiology and Immunology, 333:369-93. [PubMed link]
  148. J Gupta, MR Prausnitz (2009) Recovery of skin barrier properties after sonication in human subjects, Ultrasound in Medicine and Biology, 35:1405-1408. [PubMed link]
  149. YC Kim, FS Quan, DG Yoo, RW Compans, SM Kang, MR Prausnitz (2009) Improved influenza vaccination in the skin using vaccine-coated microneedles, Vaccine ,27:6932-6938. [PubMed link]
  150. FS Quan, YC Kim, DG Yoo, RW Compans, MR Prausnitz, SM Kang (2009) Stabilization of influenza vaccine enhances protection by microneedle delivery in the skin, PLoS ONE, 4:e7152-e7152. [PubMed link]
  151. HS Gill, SN Andrews, SK Sakthivel, A Fedanov, IR Williams, DA Garber, FH Priddy, S Yellin, MB Feinberg, SI Staprans, MR Prausnitz (2009) Selective removal of stratum corneum by microdermabrasion to increase skin permeability, European Journal of Pharmaceutical Sciences, 38:95-103. [PubMed link]
  152. J Gupta, EI Felner, MR Prausnitz (2009) Minimally invasive insulin delivery in type 1 diabetic subjects using hollow microneedles, Diabetes Technology and Therapeutics, 11:329-337. [PubMed link]
  153. Q Zhu, VG. Zarnitsyn, L Ye, Z Wen, Y Gao, L Pan, I Skountzou, HS Gill, MR Prausnitz, C Yang, RW Compans (2009) Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge, Proceedings of the National Academy of Sciences, 106:7968-7973. [PubMed link]
  154. DG Koutsonanos, MM Pilar, VG Zarnitsyn, SP Sullivan, RW Compans, MR Prausnitz, I Skountzou (2009) Transdermal influenza immunization with vaccine-coated microneedle arrays, PLoS ONE, 4:e4773. [PubMed link]
  155. J Jiang, JS Moore, HF Edelhauser, MR Prausnitz (2009) Intrascleral drug delivery to the eye using hollow microneedles, Pharmaceutical Research, 26:395-403. [PubMed link]
  156. 2008

  157. A Arora, MR Prausnitz, S Mitragotri (2008) Micro-scale devices for transdermal drug delivery, International Journal of Pharmaceutics, 364:227-236. [PubMed link]
  158. MR Prausnitz, R Langer (2008) Transdermal drug delivery, Nature Biotechnology, 26:1261-1268. [PubMed link]
  159. YB Choy, JH Park, BE McCarey, HF Edelhauser, MR Prausnitz (2008) Mucoadhesive microdiscs engineered for ophthalmic drug delivery: effect of particle geometry and formulation on preocular residence time, Investigative Ophthalmology & Visual Science, 49:4808-4815. [PubMed link]
  160. V Zarnitsyn, CA Rostad, MR Prausnitz (2008) Modeling transmembrane transport through cell membrane wounds created by acoustic cavitation, Biophysical Journal, 95:4124-4138. [PubMed link]
  161. SL Banks, RR Pinninti, HS Gill, PA Crooks, MR Prausnitz, AL Stinchcomb (2008) Flux across microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro, Pharmaceutical Research, 25:1677-1685. [PubMed link]
  162. HS Gill, DD Denson, B Burris, MR Prausnitz (2008) Effect of microneedle design on pain in human volunteers, Clinical Journal of Pain, 24:585-594. [PubMed link]
  163. YC Kim, S Late, AK. Banga, PJ Ludovice, MR Prausnitz (2008) Biochemical enhancement of transdermal delivery with magainin peptide:  modification of electrostatic interactions by changing pH, International Journal of Pharmaceutics, 362:20-28. [PubMed link]
  164. JH Park, JW Lee, YC Kim, MR Prausnitz (2008) The effect of heat on skin permeability, International Journal of Pharmaceutics 359:94-103. [PubMed link]
  165. YC Kim, PJ Ludovice, MR Prausnitz (2008) Optimization of transdermal delivery using magainin pore-forming peptide, Journal of Physics and Chemistry of Solids, 69:1560-1563. [PubMed link]
  166. HS Gill, MR Prausnitz (2008) Pocketed microneedles for drug delivery to the skin, Journal of Physics and Chemistry of Solids, 69:1537-1541. [PubMed link]
  167. YB Choy, JH Park, MR Prausnitz (2008) Mucoadhesive microparticles for ophthalmic drug delivery, Journal of Physics and Chemistry of Solids, 69:1533-1536. [PubMed link]
  168. MR Prausnitz, HS Gill, JH Park (2008) Microneedles for drug delivery, Modified Release Drug Delivery, 2nd edition, MJ Rathbone, J Hadgraft, MS Roberts and ME Lane, eds., Informa Press, New York.
  169. SP Sullivan, N Murthy, MR Prausnitz (2008) Minimally invasive protein delivery with rapidly dissolving microneedles, Advanced Materials, 20:933-938.
  170. JW Lee, JH Park, MR Prausnitz (2008) Dissolving microneedles for transdermal drug delivery, Biomaterials, 29:2113-2124. [PubMed link]
  171. YC Kim, JH Park, PJ Ludovice, MR Prausnitz, Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol (2008) International Journal of Pharmaceutics, 352:129-138. [PubMed link]
  172. DM Hallow, RA Seeger, PP Kamaev, GR Prado, MC LaPlaca, MR Prausnitz (2008) Shear-induced intracellular loading of cells with molecules by controlled microfluidics, Biotechnology and Bioengineering, 99:846-854. [PubMed link]
  173. DP Wermeling, SL Banks, DA Hudson, HS Gill, J Gupta, MR Prausnitz, AL Stinchcomb (2008) Microneedles permit transdermal delivery of a skin-impermeable medication to humans, Proceedings of the National Academy of Sciences USA ,105:2058-2063. [PubMed link]
  174. 2007

  175. HR Azencott, GF Peter, MR Prausnitz (2007) Influence of the cell wall on intracellular delivery to algal cells by electroporation and sonication, Ultrasound in Medicine and Biology, 33:1805-1817. [PubMed link]
  176. VG Zarnitsyn, PP Kamaev, MR Prausnitz (2007) Ultrasound-enhanced chemotherapy and gene delivery for glioma cells, Technology in Cancer Research & Treatment, 6:433-443. [PubMed link]
  177. YC Kim, PJ Ludovice, MR Prausnitz (2007) Transdermal delivery enhanced by magainin pore-forming peptide, Journal of Controlled Release, 122:375-383. [PubMed link]
  178. J Jiang, HS Gill, D Ghate, BE McCarey, SR Patel, HF Edelhauser, MR Prausnitz (2007) Coated microneedles for drug delivery to the eye, Investigative Ophthalmology and Visual Science, 48:4038-4043. [PubMed link]
  179. HS Gill, MR Prausnitz (2007) Does needle size matter?, Journal of Diabetes Science and Technology, 1:725-729. [PubMed link]
  180. HS Gill, MR Prausnitz (2007) Coating formulations for microneedles, Pharmaceutical Research, 24:1369-1380. [PubMed link]
  181. JH Park, SO Choi, R Kamath, YK Yoon, MG Allen, MR Prausnitz (2007) Polymer particle-based micromolding to fabricate novel polymer microstructure, Biomedical Microdevices, 9:223-234. [PubMed link]
  182. JH Park, YK Yoon, SO Choi, MR Prausnitz, MG Allen (2007) Tapered conical polymer microneedles fabricated using integrated lens technique for transdermal drug delivery, IEEE Transactions on Biomedical Engineering, 54:903-913. [PubMed link]
  183. MC Deshpande, MR Prausnitz (2007) Synergistic effect of ultrasound and PEI on DNA transfection in vitro, Journal of Controlled Release, 118:126-135. [PubMed link]
  184. DH Hallow, AD Mahajan, MR Prausnitz (2007) Ultrasonically targeted delivery into endothelial and smooth muscle cells in ex vivo arteries, Journal of Controlled Release, 118: 285-293. [PubMed link]
  185. PA Campbell, MR Prausnitz (2007) Future directions for therapeutic ultrasound, Ultrasound in Medicine and Biology, 33:657. [PubMed link]
  186. HS Gill, MR Prausnitz (2007) Coated microneedles for transdermal delivery, Journal of Controlled Release, 117:227-237. [PubMed link]
  187. 2006

  188. DM Hallow, AD Mahajan, TE McCutchen, MR Prausnitz (2006) Measurement and correlation of acoustic cavitation with cellular bioeffects, Ultrasound in Medicine and Biology, 32:1111-1122. [PubMed link]
  189. J Jiang, DH Geroski, HF Edelhauser, MR Prausnitz (2006) Measurement and prediction of lateral diffusion within human sclera, Investigative Ophthalmology and Visual Science, 47:3011-3016. [PubMed link]
  190. RK Schlicher, H Radhakrishna, TP Tolentino, RP Apkarian, V Zarnitsyn, MR Prausnitz (2006) Mechanism of intracellular delivery by acoustic cavitation, Ultrasound in Medicine and Biology, 32:915-924. [PubMed link]
  191. JH Park, MG Allen, MR Prausnitz (2006) Polymer microneedles for controlled-release drug delivery, Pharmaceutical Research, 23:1008-1019. [PubMed link]
  192. W Martanto, JS Moore, T Couse, MR Prausnitz (2006) Mechanism of fluid infusion during microneedle insertion and retraction, Journal of Controlled Release, 112:357-361. [PubMed link]
  193. EB Ghartey-Tagoe, BA Babbin, A Nusrath, AS Neish, MR Prausnitz (2006) Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation, International Journal of Pharmaceutics, 315:122-133. [PubMed link]
  194. PM Wang, M Cornwell, J Hill, MR Prausnitz (2006), Precise microinjection into skin using hollow microneedles, Journal of Investigative Dermatology, 126:1080-1087. [PubMed link]
  195. MR Prausnitz (2006) A peptide chaperone for transdermal drug delivery, Nature Biotechnology, 24:416-417. [PubMed link]
  196. HW Vesper, PM Wang, E Archibold, MR Prausnitz, GL Myers (2006) Assessment of trueness of a glucose monitor using interstitial fluid and whole blood as specimen matrix, Diabetes Technology & Therapeutics, 8:76-80. [PubMed link]
  197. W Martanto, JS Moore, O Kashlan, R Kamath, PM Wang, JM O' Neal, MR Prausnitz (2006) Microinfusion using hollow microneedles, Pharmaceutical Research, 23:104-113. [PubMed link]
  198. 2005

  199. MR Prausnitz, JA Mikszta, J Raeder-Devens (2005) Microneedles, in Percutaneous Penetration Enhancers, EW Smith and HI Maibach, eds., CRC Press, Boca Raton, FL, pp. 239-255.
  200. MR Prausnitz (2005) Assessment of microneedles for transdermal drug delivery, in Percutaneous Absorption, RL Bronaugh and HI Maibach, eds., Marcel Dekker, New York, pp. 497-507.
  201. P Prentice, A Cuschieri, K Dholakia, MR Prausnitz, P Campbell (2005) Membrane disruption by optically controlled microbubble cavitation, Nature Physics, 1:107-110.
  202. W Martanto, MK Smith, SM Baisch, EA Costner, MR Prausnitz (2005) Fluid dynamics in conically tapered microneedles, AIChE Journal, 51:1599-1607.
  203. JH Park, MG Allen, MR Prausnitz (2005) Biodegradable polymer microneedles:  fabrication, mechanics and transdermal drug delivery, Journal of Controlled Release, 104:51-66. [PubMed link]
  204. SP Davis, W Martanto, MG Allen, MR Prausnitz (2005) Hollow metal microneedles for insulin delivery to diabetic rats, IEEE Transactions on Biomedical Engineering, 52:909-915.  [PubMed link]
  205. EB Ghartey-Tagoe, JS Morgan, AS Neish, MR Prausnitz (2005) Increased permeability of intestinal epithelial monolayers mediated by electroporation, Journal of Controlled Release,, 103:177-190. [PubMed link]
  206. P Wang, M Cornwell, MR Prausnitz (2005) Minimally invasive extraction of dermal interstitial fluid for glucose monitoring using glass microneedles, Diabetes Technology & Therapeutics, 7:131-141. [PubMed link]
  207. 2004

  208. W Zhang, MR Prausnitz, A Edwards (2004) Model of transient drug diffusion into the eye, Journal of Controlled Release, 99:241-258. [PubMed link]
  209. VG Zarnitsyn, MR Prausnitz, YA Chizmadzhev (2004) Physical methods of nucleic acid delivery into cells and tissues, Biologicheskie Membrany, 21:370-388.
  210. VG Zarnitsyn, MR Prausnitz (2004) Physical parameters influencing optimization of ultrasound-mediated DNA transfection, Ultrasound in Medicine and Biology, 30:527-538.  [PubMed link]
  211. SP Davis, BJ Landis, ZH Adams, MG Allen, MR Prausnitz (2004) Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force, Journal of Biomechanics, 37:1155-1163. [PubMed link]
  212. W Martanto, SP Davis, NR Holiday, J Wang, HS Gill, MR Prausnitz (2004) Transdermal delivery of insulin using microneedles in vivo, Pharmaceutical Research, 21:947-952. [PubMed link]
  213. PJ Canatella, MM Black, DM Bonnichsen, C McKenna, MR Prausnitz (2004) Tissue electroporation: quantification and analysis of heterogeneous transport in multicellular environments, Biophysical Journal, 86:3260-3268. [PubMed link]
  214. PP Kamaev, JD Hutcheson, M Wilson, MR Prausnitz (2004) Quantification of Optison bubble size and lifetime during sonication dominant role of secondary cavitation bubbles causing acoustic bioeffects, Journal of the Acoustical Society of America, 115:1818-1825. [PubMed link]
  215. MR Prausnitz, Microneedles for transdermal drug delivery (2004) Advanced Drug Delivery Reviews, 56:581-587. [PubMed link]
  216. S-B Lee, HF Edelhauser, JS Noonan, MR Prausnitz, DH Geroski (2004) Drug delivery through the sclera: effects of thickness, hydration and sustained release systems, Experimental Eye Research, 78:599-607.  [PubMed link]
  217. MR Prausnitz, S Mitragotri, R Langer (2004) Current status and future potential of transdermal drug delivery, Nature Reviews Drug Discovery, 3:115-124. [PubMed link]
  218. EB Ghartey-Tagoe, JS Morgan, K Ahmed, AS Neish, MR Prausnitz (2004) Electroporation-mediated delivery of molecules to model intestinal epithelia, International Journal of Pharmaceutics, 270:127-138.  [PubMed link]
  219. EK Lee, RJ Gallagher, AM Campbell, MR Prausnitz (2004) Prediction of ultrasound-mediated disruption of cell membranes using machine learning techniques and statistical analysis of acoustic spectra, IEEE Transactions on Biomedical Engineering, 51:82-89. [PubMed link]
  220. 2003

  221. MR Prausnitz, D Ackley, JR Gyory (2003) Microneedles for transdermal drug delivery, in Modified Release Drug Delivery Systems, M Rathbone, J Hadgraft and M Roberts, eds., Marcel Dekker, New York, pp. 513-522.
  222. DV McAllister, PM Wang, SP Davis, J-H Park, PJ Canatella, MG Allen, MR Prausnitz (2003) Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies, Proceedings of the National Academy of Sciences (USA), 100:13755-13760. [PubMed link]
  223. HR Guzman, AJ McNamara, DX Nguyen, MR Prausnitz (2003) Bioeffects caused by changes in acoustic cavitation bubble density and cell concentration:  A unified explanation based on cell-to-bubble ratio and blast radius, Ultrasound in Medicine and Biology, 29:1211-1222.  [PubMed link]
  224. AL Coulberson, NV Hud, JM LeDoux, I Vilfan, MR Prausnitz (2003) Gene packaging with lipids, peptides and viruses inhibits transfection by electroporation in vitro, Journal of Controlled Release, 86:361-970.  [PubMed link]
  225. 2002

  226. HR Guzman, DX Nguyen, AJ McNamara, MR Prausnitz (2002) Equilibrium loading of cells with macromolecules by ultrasound:  Effects of molecular size and acoustic energy, Journal of Pharmaceutical Sciences, 91:1693-1701.  [PubMed link]
  227. 2001

  228. K Keyhani, HR Guzman, A Parsons, TN Lewis, MR Prausnitz (2001) Intracellular drug delivery using low-frequency ultrasound:  Quantification of molecular uptake and cell viability, Pharmaceutical Research, 18:1514-1520. [PubMed link]
  229. PJ Canatella, MR Prausnitz (2001) Prediction and optimization of gene transfection and drug delivery by electroporation, Gene Therapy, 8:1464-1469. [PubMed link]
  230. A Edwards, MR Prausnitz (2001) Predicted permeability of the cornea to topical drugs, Pharmaceutical Research, 18:1497-1508.  [PubMed link]
  231. MR Prausnitz (2001) Overcoming skin’s barrier:  The search for effective and user-friendly drug delivery, Diabetes Technology & Therapeutics, 3:233-236.  [PubMed link]
  232. SA Cochran, MR Prausnitz (2001) Sonoluminescence as an indicator of cell membrane disruption by acoustic cavitation, Ultrasound in Medicine and Biology, 27:841-850. [PubMed link]
  233. HR Guzman, DX Nguyen, S Kahn, MR Prausnitz (2001) Ultrasound-mediated disruption of cell membranes II:  Heterogeneous effects on cells, Journal of the Acoustical Society of America, 110:597-606. [PubMed link]
  234. HR Guzman, DX Nguyen, S Kahn, MR Prausnitz (2001) Ultrasound-mediated disruption of cell membranes I:  Quantification of molecular uptake and cell viability, Journal of the Acoustical Society of America, 110:588-596. [PubMed link]
  235. S Kaushik, A Krishnan, MR Prausnitz, PJ Ludovice (2001) Magainin-mediated disruption of stratum corneum lipid vesicles, Pharmaceutical Research, 18:894-896.  [PubMed link]
  236. S Kaushik, AH Hord, DD Denson, DV McAllister, S Smitra, MG Allen, MR Prausnitz (2001) Lack of pain associated with microfabricated microneedles, Anesthesia & Analgesia, 92:502-504.  [PubMed link]
  237. PJ Canatella, JF Karr, JA Petros, MR Prausnitz (2001) Quantitative study of electroporation-mediated molecular uptake and cell viability, Biophysical Journal, 80:755-764. [PubMed link]
  238. 2000

  239. MR Prausnitz, MJ Bradley (2000) Effective communication for professional engineering: Beyond problem sets and lab reports, Chemical Engineering Education, 34:234-237.  [PubMed link]
  240. DV McAllister, MG Allen, MR Prausnitz (2000) Microfabricated microneedles for gene and drug delivery, Annual Review of Biomedical Engineering, 2:289-313. [PubMed link]
  241. 1999

  242. U Pliquett, MR Prausnitz (1999) Electrical impedance spectroscopy for rapid and non-invasive analysis of skin electroporation, in Electrically Mediated Delivery of Molecules to Cells — Electrochemotherapy, Electrogenetherapy, and Transdermal Delivery by Electroporation, MJ Jaroszeski, R Gilbert, and R Heller, eds., Humana Press, Totowa, NJ, pp. 377-406.
  243. MR Prausnitz, U Pliquett, R Vanbever (1999) Mechanistic studies of skin electroporation using biophysical methods, in Electrically Mediated Delivery of Molecules to Cells — Electrochemotherapy, Electrogenetherapy, and Transdermal Delivery by Electroporation, MJ Jaroszeski, R Gilbert, and R Heller, eds., Humana Press, Totowa, NJ, pp. 214-235.
  244. DE Rudnick, JS Noonan, DH Geroski, MR Prausnitz, HF Edelhauser (1999) The effect of intraocular pressure on human and rabbit scleral permeability, Investigative Ophthalmology & Visual Science, 40:3054-3058. [PubMed link]
  245. MR Prausnitz (1999) A practical assessment of transdermal drug delivery by skin electroporation, Advanced Drug Delivery Reviews, 35:61-76. [PubMed link]
  246. 1998

  247. MR Prausnitz (1998) Electroporation, in Electronically-Controlled Drug Delivery, B Berner and SM Dinh, eds., CRC Press, Boca Raton, FL, pp. 185-214
  248. MR Prausnitz, JS Noonan (1998) Permeability of cornea, sclera and conjunctiva: A literature analysis for drug delivery to the eye, Journal of Pharmaceutical Sciences, 87:1479-1488. [PubMed link]
  249. MR Prausnitz, A Edwards, JS Noonan, DE Rudnick, HF Edelhauser, DH Geroski (1998) Measurement and prediction of transient transport across sclera for drug delivery to the eye, Industrial and Engineering Chemistry Research, 37:2903-2907.
  250. J Liu, T Lewis, MR Prausnitz (1998) Non-invasive assessment and control of ultrasound-mediated membrane permeabilization, Pharmaceutical Research, 15:918-924. [PubMed link]
  251. A Banga, MR Prausnitz (1998) Assessing the potential of skin electroporation for the delivery of protein- and gene-based drugs, Trends in Biotechnology, 16:408-412. [PubMed link]
  252. S Henry, DV McAllister, MG Allen, MR Prausnitz (1998) Microfabricated microneedles: A novel approach to transdermal drug delivery, Journal of Pharmaceutical Sciences, 87:922-925. [PubMed link]
  253. MR Prausnitz (1998) COMET: An open-ended, hands-on design project for chemical engineering sophomores, Chemical Engineering Education, 32:20-23, 45.
  254. A Edwards, MR Prausnitz (1998) Fiber matrix model of sclera and corneal stroma for drug delivery to the eye AIChE Journal, 44:214-225. [PubMed link]
  255. 1997

  256. MR Prausnitz (1997) Transdermal delivery of proteins:  recent advances by modification of skin's barrier properties, in Therapeutic Protein and Peptide Formulation and Delivery, Z Shahrokh, V Sluzky, J. Cleland, S Shire, and T Randolph, eds., American Chemical Society, Washington, DC, pp. 124-153.
  257. MR Prausnitz (1997) Reversible skin permeabilization for transdermal delivery of macromolecules, Critical Reviews in Therapeutic Drug Carrier Systems, 14:455-483. [PubMed link]
  258. JC Weaver, R Vanbever, T Vaughan, MR Prausnitz (1997) Heparin alters transdermal transport associated with electroporation, Biochemical and Biophysical Research Communications, 234:637-640. [PubMed link]
  259. R Vanbever, MR Prausnitz, V Préat (1997) Macromolecules as novel transdermal transport enhancers for skin electroporation, Pharmaceutical Research, 14:638-644. [PubMed link]
  260. 1996

  261. MR Prausnitz (1996) Do high-voltage pulses cause changes in skin structure?, Journal of Controlled Release, 40:321-326. [PubMed link]
  262. MR Prausnitz, JA Gimm, JC Weaver, RH Guy, R Langer, C Cullander (1996) Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures, Journal of Pharmaceutical Sciences, 85:1363-1370. [PubMed link]
  263. MR Prausnitz, CS Lee, CH Liu, JC Pang, T-P Singh, R Langer, JC Weaver (1996) Transdermal transport efficiency during skin electroporation and iontophoresis, Journal of Controlled Release, 38:205-217.
  264. MR Prausnitz (1996) The effects of current applied to the skin:  a review for transdermal drug delivery, Advanced Drug Delivery Reviews, 18:395-425.
  265. 1995

  266. MR Prausnitz, VG Bose, R Langer and JC Weaver (1995) Electroporation, Percutaneous Penetration Enhancers, HI Maibach and EW Smith, eds., CRC Press, Boca Raton, FL, pp. 393-405.
  267. MR Prausnitz, I Cordero and A Levenson (1995) Focus on: ORBIS International flying eye hospital, department of technical services, Journal of Clinical Engineering, 20:388-393. [PubMed link]
  268. MR Prausnitz, ER Edelman, JA Gimm, R Langer, JC Weaver (1995) Transdermal delivery of heparin by skin electroporation, Bio/Technology, 13:1205-1209. [PubMed link]
  269. DA Edwards, MR Prausnitz, R Langer, JC Weaver (1995) Analysis of enhanced transdermal transport by skin electroporation, Journal of Controlled Release, 34:211-221.
  270. MR Prausnitz, JD Corbett, JA Gimm, DE Golan, R Langer, JC Weaver (1995) Millisecond measurement of transport during and after an electroporation pulse, Biophysical Journal, 68:1864-1870. [PubMed link]
  271. U Pliquett, MR Prausnitz, YA Chizmadzhev, JC Weaver (1995) Measurement of rapid release kinetics for drug delivery, Pharmaceutical Research, 12:549-555. [PubMed link]
  272. 1994

  273. MR Prausnitz, U Pliquett, R Langer, JC Weaver (1994) Rapid temporal control of transdermal drug delivery by electroporation, Pharmaceutical Research, 11:1834-1837. [PubMed link]
  274. MR Prausnitz, CD Milano, JA Gimm, R Langer, JC Weaver (1994) Quantitative study of molecular transport due to electroporation:  uptake of bovine serum albumin by erythrocyte ghosts, Biophysical Journal, 66:1522-1530. [PubMed link]
  275. 1993

  276. MR Prausnitz, DS Seddick, AA Kon, VG Bose, S Frankenburg, SN Klaus, R Langer, JC Weaver (1993) Methods for in vivo tissue electroporation using surface electrodes, Drug Delivery, 1:125-131.
  277. MR Prausnitz, BS Lau, CD Milano, S Conner, R Langer, JC Weaver (1993) A quantitative study of electroporation showing a plateau in net molecular transport, Biophysical Journal, 65:414-422. [PubMed link]
  278. MR Prausnitz, VG Bose, R Langer, JC Weaver (1993) Electroporation of mammalian skin:  a mechanism to enhance transdermal drug delivery, Proceedings of the National Academy of Sciences (USA), 90:10504-10508. [PubMed link]